And as some spake of the temple, how it was adorned with goodly stones and gifts, he said, As for these things which ye behold, the days will come, in the which there shall not be left one stone upon another, that shall not be thrown down. Luke 21:5-6
I think one of the most significant events that are overlooked is the destruction of the Temple. Jesus predicted that this day would come when the Temple in Jerusalem was destroyed, and it happened in 70 A.D.
Now to understand the significance of this you need to understand the Temple of God. This was the holiest place on Earth, the only place where the Spirit of God dwelled. The only place where you can get atonement for your sin, the only place where the Ark of the Covenant lived.
But Jesus was about to change all of this, as Jesus said Destroy this temple in 3 days and I will raise it up (John 2:19) The New Covenant no longer required a Temple because we become the Temple of God by becoming Born Again through Jesus Christ
And they asked him, saying, Master, but when shall these things be? and what sign will there be when these things shall come to pass? Luke 21:7
The disciples wanted to know, “When will this happen”? After the Resurrection it turned the whole world upside down. Why? Because Jesus defeated Sin and Death, Satan no longer has a hold of us. So what happened? The whole world went into chaos, even today we still see the chaos.
But the Romans fulfilled this prophecy of destroying the Temple in Jerusalem, and it was never rebuilt again. Why? Because the Old Covenant has been fulfilled, the New Covenant is we are the Temples of God and the Holy Spirit lives inside of us! (1 Corinthians 6:19-20)